HUMAN HEALTH

We produce bacterial and viral vaccines under a strict innovative policy to achieve the best results

CDMO SERVICES

END-TO-END
CDMO

  • Bacterial & viral Vaccines up to BSL-2
  • Aseptic processing systems
  • Process development/optimization
  • Scale-up and cGMP manufacturing
  • Aseptic filling into vials
  • Lyophilization (clinical trial material and large scale)
  • Quality control testing: microbiological, sterility and non-sterility, chemical, physical and biological
  • Labelling & packaging
  • DS & DP release
  • Storage: (+2-8°C), (-20°C), (-30°C), (-80°C)

ONE-STOP SHOP ORGANIZATION

Development, clinical phase I-III and commercial manufacturing

COVID-19

CZ Vaccines decided to collaborate actively on the urgent development of solutions against coronavirus disease COVID19 through our research and manufacturing capabilities in several projects.

cGMP
PRODUCTION CAPABILITIES

  • cGMP preparation and control of Master and Working Seed Banks of cells, virus and bacteria
  • Roller bottles, cell Factory & wave bioreactor
  • Single use bioreactors: up to 2,000L
  • Stainless steel bioreactors: up to 2,000L
  • Single use blending mixers: 2 × 3,000L
  • Stainless steel vessels: 4 × 6,000L
  • State-of the art purification processes: Chromatography (ÄKTA ready), centrifugation, ultrafiltration, diafiltration, tangential flow filtration

CDMO
FILL & FINISH CAPABILITIES

  • Liquid and lyophilised products up to BSL-2
  • 4 filling machines: 6,000 vials/hour – 2 × 12,000 vials/hour – 24,000 vials/hour
  • 2 freeze dryer: up to 24,000 vials per run, and up to 180,000 – 200,000 vials per run
  • Component size: 2R-10R-20R
  • Manual & automatic visual inspection
  • Labelling & packaging